Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about MIRO: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| Mitochondrial-Derived Vesicle Biogenesis | activates | process | 0.95 |
| Mitochondrial-Derived Vesicle Biogenesis | mediates | process | 0.90 |
| Mitochondria | expressed_in | cell_type | 0.80 |
| KINESIN-1 | binds | protein | 0.80 |
| Source | Relation | Type | Str |
|---|---|---|---|
| MIRO1 | involved_in | protein | 0.80 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| Miro1-Mediated Mitochondrial Trafficking Enhancement Therapy | 0.426 | neurodegeneration | Mitochondrial transfer between neurons a |
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| Dihuang Yinzi ameliorates post-stroke depression through Miro1 ubiquitination-de [PMID:41850637] | Chang H, Ji Z, Sun Q, Zhou S, Yang Z, Qu | Journal of ethnopharmacology | 2026 | 0 |
| Miro1 protects against brain injury after CPR in rats by enhancing the effect of [PMID:41153049] | Ma X, Shen M, Hu J, Zhu J, Wang Z, Zhou | Stem cell research & therapy | 2025 | 0 |
| Parkinson's disease mutant Miro1 causes mitochondrial dysfunction and dopaminerg [PMID:39913247] | Chemla A, Arena G, Sacripanti G, Barmpa | Brain : a journal of neurology | 2025 | 0 |
| Generation of two induced pluripotent stem cell lines and the corresponding isog [PMID:37364399] | Chemla A, Arena G, Onal G, Walter J, Ber | Stem cell research | 2023 | 0 |
| Generation of two induced pluripotent stem cell lines and the corresponding isog [PMID:37003181] | Chemla A, Arena G, Saraiva C, Berenguer- | Stem cell research | 2023 | 0 |
| Harlequin syndrome associated with thoracic epidural anaesthesia. [PMID:35118419] | Persson RM, Tellnes K, Hoven H, Haaverst | Anaesthesia reports | 2022 | 0 |
| Transmission dynamics of a linear vanA-plasmid during a nosocomial multiclonal o [PMID:34285270] | Fujiya Y, Harada T, Sugawara Y, Akeda Y, | Scientific reports | 2021 | 0 |
| Generation of R272Q, S156A and K572R RHOT1/Miro1 point mutations in iPSCs from a [PMID:34359002] | Schwarz L, Casadei N, Fitzgerald JC | Stem cell research | 2021 | 0 |
| High resolution spatiotemporal patterns of seawater temperatures across the Beli [PMID:33199700] | Helmuth B, Leichter JJ, Rotjan RD, Casti | Scientific data | 2020 | 0 |
| The Emerging Role of RHOT1/Miro1 in the Pathogenesis of Parkinson's Disease. [PMID:33041957] | Grossmann D, Berenguer-Escuder C, Chemla | Frontiers in neurology | 2020 | 0 |
| DPYD*6 plays an important role in fluoropyrimidine toxicity in addition to DPYD* [PMID:30723313] | Del Re M, Cinieri S, Michelucci A, Salva | The pharmacogenomics journal | 2019 | 0 |
| Genome Sequence of the K139-Like Phage VcP032 Originating from the Vibrio choler [PMID:27445393] | Jäckel C, Strauch E, Hammerl JA | Genome announcements | 2016 | 0 |
| Clarithromycin as a chiral selector for enantioseparation of basic compounds in [PMID:25100556] | Lebedeva MV, Prokhorova AF, Shapovalova | Electrophoresis | 2014 | 0 |
| Medial prefrontal D1 dopamine neurons control food intake. [PMID:24441680] | Land BB, Narayanan NS, Liu RJ, Gianessi | Nature neuroscience | 2014 | 0 |
| DISC1 complexes with TRAK1 and Miro1 to modulate anterograde axonal mitochondria [PMID:24092329] | Ogawa F, Malavasi EL, Crummie DK, Eykele | Human molecular genetics | 2014 | 0 |