protein

MIRO2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about MIRO2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

12Connections
0Hypotheses
0Analyses
10Outgoing
2Incoming

Summary

MIRO2 is a protein involved in neurodegeneration research. Key relationships include: activates, therapeutic target, associated with. Associated with Ms. Connected to 10 entities in the SciDEX knowledge graph.

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🔬 Protein Info
Gene SymbolMIRO2
Full NameMIRO2
Chromosome16p13.3.
Protein TypeGene
Functionencodes a tail-anchored outer-membrane GTPase.
Molecular Weight68 kDa
Amino Acids618 aa
PathwaysMitochondrial-Derived Vesicle Biogenesis
NCBI Gene IDSearch NCBI
GeneCardsMIRO2
Human Protein AtlasMIRO2
Associated Diseasesneurodegeneration
InteractionsMIRO1
KG Connections12 knowledge graph edges
DatabasesGeneCardsUniProtHPASTRING

Wiki Pages (16)

Knowledge base pages for this entity

Canonical Page

MIRO2 Gene

gene · 1308 words

Axonal Transport Rescue Therapy for Neurodegeneration

idea · 2890 words

KIF28P — Kinesin Family Member 28, Pseudogene

gene · 2824 words

Axonal Transport Defects in Neurodegenerative Diseases

mechanism · 2216 words

protein-trafficking-pathways

mechanism · 2007 words

Mitophagy Receptor Pathway in Neurodegeneration

mechanism · 1868 words

Pathway Diagram

graph TD
    MIRO2["<b>MIRO2</b>"]
    Ms{"Ms"}
    MIRO2 -->|"regulates"| Ms
    MIRO2 -->|"therapeutic target"| Ms
    MIRO2 -->|"activates"| Ms
    MIRO1["MIRO1"]
    MIRO2 -->|"associated with"| MIRO1
    MIRO2 -->|"activates"| MIRO1
    Immune_Response(["Immune Response"])
    MIRO2 -->|"therapeutic target"| Immune_Response
    SACS["SACS"]
    MIRO2 -->|"associated with"| SACS
    neurodegeneration["neurodegeneration"]
    MIRO2 -->|"implicated in"| neurodegeneration
    MIRO1 -->|"activates"| MIRO2
    style MIRO2 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (10)

TargetRelationTypeStr
mitochondrial-derived vesicle biogenesisdrivesprocess0.95
Mitochondrial-Derived Vesicle Biogenesisactivatesprocess0.95
Mitochondrial-Derived Vesicle Biogenesispromotesprocess0.95
Msregulatesdisease0.65
Mstherapeutic_targetdisease0.65

Incoming (2)

SourceRelationTypeStr
MIRO1interacts_withentity0.85
MIRO1activatesgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found