Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about MT-ND1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | MT |
| Function | Cytochrome b is a key component of Complex III (ubiquinol-cytochrome c reductase), which catalyzes the transfer of electrons from ubiquinol to cytochrome c. |
| GeneCards | MT |
| Human Protein Atlas | MT |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
MT_ND1["MT-ND1"]
oxidative_phosphorylation["oxidative phosphorylation"]
PS_COOH["PS-COOH"]
MT_ND1 -->|"involved in"| oxidative_phosphorylation
PS_COOH -->|"downregulates"| MT_ND1
style MT_ND1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#fff
style oxidative_phosphorylation fill:#1a3a1a,stroke:#81c784,stroke-width:2px,color:#fff
style PS_COOH fill:#1a1a2e,stroke:#888,stroke-width:2px,color:#fff| Target | Relation | Type | Str |
|---|---|---|---|
| ds-83b31ef18d49 | provides_data_for | dataset | 1.00 |
| oxidative phosphorylation | involved_in | pathway | 0.90 |
| Complex_I | component_of | protein_complex | 0.50 |
| benchmark_ot_ad_answer_key:MT-ND1 | data_in | dataset_row | 0.00 |
| Source | Relation | Type | Str |
|---|---|---|---|
| ds-83b31ef18d49 | data_in | dataset | 1.00 |
| PS-COOH | downregulates | compound | 0.90 |
| h-420db533 | targets_gene | hypothesis | 0.90 |
| Ps-Cooh | downregulates | compound | 0.80 |
| h-420db533 | targets | hypothesis | 0.35 |
| benchmark_ot_ad_answer_key:MT-ND1 | data_in | dataset_row | 0.00 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
neurodegeneration | 2026-04-03 | 14 hypotheses Top: 0.622
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||