gene

NARS2

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about NARS2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Mitochondrial Asparaginyl-tRNA Synthetase - essential for mitochondrial translation with implications in Leigh syndrome, Alzheimer's, and Parkinson's diseases

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🧬 Gene Info

Gene Symbol	NARS2
Full Name	Mitochondrial Asparaginyl-tRNA Synthetase
Chromosome	11q14.1
Primary Expression	all tissues with high energy demands:
Molecular Weight	56 kDa
UniProt ID	[Q9HBJ5](https://www.uniprot.org/uniprotkb/Q9HBJ5/entry)
Ensembl ID	ENSG00000137558
GeneCards	NARS2
Human Protein Atlas	NARS2
Complex I subunits	ND1, ND2, ND3, ND4, ND4L, ND5, ND6
Complex III subunits	CYTB
Complex IV subunits	COX1, COX2, COX3
Complex V subunits	ATP6, ATP8
Associated Diseases	Alzheimer's disease, Parkinson's disease
Databases	GeneCards NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

NARS2 Gene

gene · 1165 words

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Pathway Diagram

graph TD
    NARS2["NARS2"]
    neurodegeneration["neurodegeneration"]
    NARS2 -->|"implicated_in"| neurodegeneration
    style NARS2 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning NARS2 in their description or question text

No additional research found