gene

NCK2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about NCK2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

2Connections

0Hypotheses

0Analyses

1Outgoing

1Incoming

0Experiments

0Debates

Summary

NCK2 adaptor protein in neuronal signaling, cytoskeletal dynamics, and neurodegeneration

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🧬 Gene Info

Gene Symbol	NCK2
Chromosome	2q36.3
Protein Type	Adaptor Protein
Function	is a member of the NCK family of cytoplasmic adaptor proteins that play critical roles in signal transduction, cytoskeletal reorganization, and cell migration.
Amino Acids	380 aa
Pathways	Receptor
UniProt ID	O43571
NCBI Gene ID	8449
Ensembl ID	ENSG00000170088
GeneCards	NCK2
Human Protein Atlas	NCK2
Associated Diseases	Alzheimer's disease, Parkinson's disease
KG Connections	2 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: NCK2 — AlphaFold O43571 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

NCK2 Gene

gene · 2451 words

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Pathway Diagram

graph TD
    NCK2["NCK2"]
    neurodegeneration["neurodegeneration"]
    NCK2 -->|"implicated_in"| neurodegeneration
    style NCK2 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (1)

Target	Relation	Type	Str
ds-83b31ef18d49	provides_data_for	dataset	1.00

Incoming (1)

Source	Relation	Type	Str
ds-83b31ef18d49	data_in	dataset	1.00

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning NCK2 in their description or question text

No additional research found