protein

NLRC5PROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about NLRC5PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Hypotheses

0Analyses

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0Experiments

No summary available yet. View on Wiki →

🔬 Protein Info

Gene Symbol	NLRC5
Full Name	NLR Family CARD Domain Containing 5
Chromosome	16p13.13
Protein Family	NLR family, NOD-like receptor family
Function	regulating MHC class I expression and innate immunity
Primary Expression	Ubiquitous, high in immune cells
Subcellular Localization	Cytoplasm, Nucleus
Molecular Weight	~204 kDa (1,866 amino acids)
Amino Acids	2000 aa
Pathways	NF-κB
UniProt ID	Q86TI2
Ensembl ID	ENSG00000148488
OMIM	613851
GeneCards	NLRC5
Human Protein Atlas	NLRC5
Associated Diseases	Infectious Disease, Inflammatory Disease
Known Drugs/Compounds	Heme, PAMP
Interactions	CD8, IRF1, CIITA, NPM1, NLRP12, Panoptosome
KG Connections	85 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: NLRC5PROTEIN — AlphaFold Q86TI2 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

nlrc5-protein

protein · 4393 words

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Pathway Diagram

graph TD
    NLRC5PROTEIN["NLRC5PROTEIN"]
    neurodegeneration["neurodegeneration"]
    NLRC5PROTEIN -->|"implicated_in"| neurodegeneration
    style NLRC5PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found