Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about NOMO1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Target | Relation | Type | Str |
|---|---|---|---|
| ER_homeostasis | regulates | process | 0.50 |
| neurodegeneration | associated_with | disease | 0.50 |
| PSMC | co_associated_with | gene | 0.40 |
| Source | Relation | Type | Str |
|---|---|---|---|
| h-9a721223 | targets | hypothesis | 0.45 |
| ACE | co_associated_with | gene | 0.40 |
| APP | co_associated_with | gene | 0.40 |
| CXCL10 | co_associated_with | gene | 0.40 |
| GPX4 | co_associated_with | gene | 0.40 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| NOMO1-Mediated Neuronal Resilience Enhancement | 0.412 | neurodegeneration | Gene expression changes in aging mouse b |
Scientific analyses that reference this entity
neurodegeneration | 2026-04-03 | 34 hypotheses Top: 0.692
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| Mesothelin Promotes Acute Myeloid Leukemia Progression through LYN-dependent Sig [PMID:41866035] | Faust JR, Hamill D, Kolb EA, Stevens AM, | J Biol Chem | 2026 | 0 |