Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about PET117: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Comprehensive gene page for PET117 (Cytochrome C Oxidase Assembly Factor PET117), a mitochondrial protein essential for complex IV assembly with implications for neurodegenerative diseases
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| Gene Symbol | PET117 |
| Full Name | Cytochrome C Oxidase Assembly Factor |
| Aliases | Cytochrome C Oxidase Assembly Factor PET117 |
| Function | High metabolic demands of action potentials |
| Ensembl ID | ENSG00000157103 |
| GeneCards | PET117 |
| Human Protein Atlas | PET117 |
| Transmembrane domain | Anchors the protein to the inner mitochondrial membrane |
| Matrix-facing domain | Contains functional regions for assembly factor activity |
| Associated Diseases | Alzheimer's disease, Parkinson's disease |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
PET117["PET117"]
neurodegeneration["neurodegeneration"]
PET117 -->|"implicated_in"| neurodegeneration
style PET117 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning PET117 in their description or question text
No additional research found