Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about PEX16: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
PEX16 encodes peroxin-16, a critical peroxisomal membrane protein required for peroxisome biogenesis and implicated in neurodegenerative diseases
| Gene Symbol | PEX16 |
| Full Name | Peroxisome Biogenesis Factor 16 |
| Chromosome | 11p11.2 |
| Protein Family | PEX proteins, peroxisome biogenesis factors |
| Function | encodes an essential peroxisomal membrane protein critical for early stages of peroxisome biogenesis. |
| Subcellular Localization | Peroxisomal membrane |
| Amino Acids | 336 aa |
| UniProt ID | Q9Y5Y5 |
| NCBI Gene ID | 5494 |
| Ensembl ID | ENSG00000121653 |
| OMIM | 603460 |
| GeneCards | PEX16 |
| Human Protein Atlas | PEX16 |
| Encoded Protein | Peroxin-16 |
| Protein Length | 336 amino acids |
| Associated Diseases | Alzheimer's disease, Parkinson's disease |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
PEX16["PEX16"]
neurodegeneration["neurodegeneration"]
PEX16 -->|"implicated_in"| neurodegeneration
style PEX16 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| No outgoing edges | |||
| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity