Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about POLD4: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
DNA Polymerase Delta Subunit 4 - the p12 regulatory subunit essential for functional Pol δ complex formation, genomic stability, and neuronal DNA repair
| Gene Symbol | POLD4 |
| Full Name | DNA Polymerase Delta Subunit 4[@pold2019] |
| Aliases | P12, POLδ4 |
| Chromosome | 11q13.2 |
| Protein Family | DNA polymerases (Pol δ family) |
| Molecular Weight | 12 kDa |
| Amino Acids | 110 aa |
| Exons | 4 |
| Gene Type | Protein coding |
| UniProt ID | Q9NPJ3 |
| NCBI Gene ID | 57804 |
| Ensembl ID | ENSG00000141540 |
| OMIM | 611415 |
| GeneCards | POLD4 |
| Human Protein Atlas | POLD4 |
| Associated Diseases | Alzheimer's disease, Parkinson's disease |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
POLD4["POLD4"]
neurodegeneration["neurodegeneration"]
POLD4 -->|"implicated_in"| neurodegeneration
style POLD4 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity