Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about PPP2R5A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Protein Phosphatase 2A Regulatory Subunit B56 Alpha - key regulator of tau dephosphorylation and cell signaling
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| Gene Symbol | PPP2R5A |
| Full Name | Protein Phosphatase 2A Regulatory Subunit B56 Alpha |
| Chromosome | 1q41 |
| Function | encodes a protein of approximately 526 amino acids with a molecular weight of ~57 kDa. |
| Molecular Weight | 57 kDa |
| Amino Acids | 526 aa |
| Pathways | Wnt signaling |
| UniProt ID | [Q16586](https://www.uniprot.org/uniprot/Q16586) |
| Ensembl ID | ENSG00000100994 |
| GeneCards | PPP2R5A |
| Human Protein Atlas | PPP2R5A |
| Associated Diseases | Alzheimer's disease, Parkinson's disease |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
PPP2R5A["PPP2R5A"]
neurodegeneration["neurodegeneration"]
PPP2R5A -->|"implicated_in"| neurodegeneration
style PPP2R5A fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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Scientific publications cited in analyses involving this entity
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning PPP2R5A in their description or question text
No additional research found