gene

PTBP2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about PTBP2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Hypotheses

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Summary

Comprehensive guide to PTBP2 alternative splicing regulation in neurons and its role in neurodegenerative diseases

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🧬 Gene Info

Gene Symbol	PTBP2
Full Name	Polypyrimidine Tract Binding Protein 2
Chromosome	5q31.2
Protein Family	PTB family (RNA binding proteins)
Function	RNA recognition motifs (RRMs): Four RRMs (RRM1-4) bind to polypyrimidine tracts in target pre-mRNAs
Primary Expression	Ubiquitous
UniProt ID	Q9UKJ3
NCBI Gene ID	58160
Ensembl ID	ENSG00000117569
GeneCards	PTBP2
Human Protein Atlas	PTBP2
Associated Diseases	Alzheimer's disease, Parkinson's disease, ALS
Databases	GeneCards HPA STRING

🔮 Predicted Structure: PTBP2 — AlphaFold Q9UKJ3 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

PTBP2 - Polypyrimidine Tract Binding Protein 2

gene · 3381 words

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Pathway Diagram

graph TD
    PTBP2["PTBP2"]
    neurodegeneration["neurodegeneration"]
    PTBP2 -->|"implicated_in"| neurodegeneration
    style PTBP2 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning PTBP2 in their description or question text

No additional research found