Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about Pathological Aggregation: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| TARDBP | associated_with | protein | 0.90 |
| FUS | associated_with | protein | 0.90 |
| FUS | involved_in | protein | 0.90 |
| phase separation behaviors | modulates | process | 0.50 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| RBM45 Liquid-Liquid Phase Separation Dominance Hijacks RNA P | 0.868 | als | - |
| TDP-43 Liquid-Liquid Phase Separation Dominance in Stress Gr | 0.650 | alzheimers | - |
Scientific analyses that reference this entity
neurodegeneration | 2026-04-08 | 5 hypotheses Top: 0.280
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
Hypotheses and analyses mentioning Pathological Aggregation in their description or question text
No additional research found