entity

Phase Transition

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about Phase Transition: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

3Connections
5Hypotheses
0Analyses
0Outgoing
3Incoming
0Experiments
0Debates

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Outgoing (0)

TargetRelationTypeStr
No outgoing edges

Incoming (3)

SourceRelationTypeStr
FUSinvolved_inprotein0.95
TDP43associated_withprotein0.88
Tardbpinvolved_inprotein0.85

Targeting Hypotheses (5)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
Stress-granule RNA-binding protein phase transition across A 0.780 multi Cross-disease neurodegeneration mechanis
Arginine Methylation Loss on FUS RGG Domains Drives Irrevers 0.680 als Biophysical Determinants Shifting FUS/TD
Rational design of small molecules targeting TDP-43 liquid-t 0.510 neurodegeneration Test
PS Externalization Requires Tau Aggregation-Phase Transition 0.000 - Does tau aggregation specifically cause
Phase Transition Kinetics Modulators 0.000 - TDP-43 phase separation therapeutics for

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

ExperimentTypeDiseaseScoreFeasibilityModelStatusEst. Cost
No experiments found

Related Papers (3)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Prom [PMID:28817800] ["Mackenzie Ian R", "Nicholson Alexandra Neuron 2017 0
Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem prote [PMID:23455423] Unknown Nature 2013 0
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic latera [PMID:17023659] Unknown Science (New York, N.Y.) 2006 0

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning Phase Transition in their description or question text

No additional research found