Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about RAB3D: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
RAB3D is a synaptic vesicle-associated Rab GTPase involved in regulated secretion, neurotransmitter release, and neuronal plasticity. It plays roles in Alzheimer's and Parkinson's disease models.
| Gene Symbol | RAB3D |
| Full Name | RAB3D, Member RAS Oncogene Family |
| Chromosome | 19p13.2 |
| Function | encodes a member of the Rab GTPase family that is predominantly expressed in neurons and neuroendocrine cells, where it plays critical roles in regulated secretion and synaptic vesicle trafficking. |
| Primary Expression | neurons and neuroendocrine cells, where it plays critical roles in regulated secretion and synaptic vesicle trafficking |
| Amino Acids | 220 aa |
| Ensembl ID | ENSG00000131899 |
| GeneCards | RAB3D |
| Human Protein Atlas | RAB3D |
| Associated Diseases | Alzheimer's disease, Parkinson's disease |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
RAB3D["RAB3D"]
neurodegeneration["neurodegeneration"]
RAB3D -->|"implicated_in"| neurodegeneration
style RAB3D fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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| No papers found | ||||