gene

REEP5

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about REEP5: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

4Connections
0Hypotheses
0Analyses
2Outgoing
2Incoming

No summary available yet. View on Wiki →

🧬 Gene Info
Gene SymbolREEP5
Full NameREEP5
Chromosome5q
Protein TypeGene
Functionis an important component in the neurobiology of neurodegenerative diseases.
PathwaysMitochondrial Function
NCBI Gene IDSearch NCBI
GeneCardsREEP5
Human Protein AtlasREEP5
Associated Diseasesneurodegeneration
InteractionsMFN1
KG Connections4 knowledge graph edges
DatabasesGeneCardsUniProtHPASTRING

Wiki Pages (7)

Knowledge base pages for this entity

Canonical Page

REEP5 Gene

gene · 898 words

Betz Cells in Hereditary Spastic Paraplegia

cell · 2327 words

REEP6 - REEP6 (Receptor Expression Enhancing Protein 6)

gene · 2075 words

Atlastin-1 Protein

redirect · 657 words

Upper Motor Neurons in Primary Lateral Sclerosis

cell · 645 words

RTN1 Protein (Reticulon-1)

protein · 630 words

Pathway Diagram

graph TD
    REEP5["REEP5"]
    MFN1["MFN1"]
    REEP5 -->|"interacts with"| MFN1
    Mitochondrial_Function["Mitochondrial Function"]
    REEP5 -->|"regulates"| Mitochondrial_Function
    neurodegeneration["neurodegeneration"]
    REEP5 -->|"implicated in"| neurodegeneration
    MFN2["MFN2"]
    MFN2 -->|"regulates"| REEP5
    MICROTUBULES["MICROTUBULES"]
    MICROTUBULES -->|"regulates"| REEP5
    style REEP5 fill:#1a237e,stroke:#4fc3f7,color:#4fc3f7

Outgoing (2)

TargetRelationTypeStr
MFN1interacts_withgene0.60
Mitochondrial Functionregulatespathway0.60

Incoming (2)

SourceRelationTypeStr
MFN2regulatesgene0.60
MICROTUBULESregulatesgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found