Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SEPT9: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
SEPT9 is a GTP-binding protein involved in cytoskeleton organization, cell division, and implicated in Parkinson's disease and neurodegeneration.
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| Gene Symbol | SEPT9 |
| Full Name | Septin 9 |
| Chromosome | 17q25.3 |
| Protein Family | Septin GTPase family |
| Function | is a member of the septin family of GTP-binding proteins involved in cytoskeleton organization and cell division[@mostowy2014]. |
| Primary Expression | Ubiquitous, high in brain |
| UniProt ID | [Q9UQD0](https://www.uniprot.org/uniprot/Q9UQD0) |
| Ensembl ID | ENSG00000184640 |
| OMIM | 606551 |
| GeneCards | SEPT9 |
| Human Protein Atlas | SEPT9 |
| Associated Diseases | Parkinson's disease, Alzheimer's disease |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
SEPT9["SEPT9"]
neurodegeneration["neurodegeneration"]
SEPT9 -->|"implicated_in"| neurodegeneration
style SEPT9 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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Scientific publications cited in analyses involving this entity
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning SEPT9 in their description or question text
No additional research found