gene

SETD1B

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SETD1B: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

0Connections

0Hypotheses

0Analyses

0Outgoing

0Incoming

0Experiments

0Debates

Summary

SETD1B is a histone H3K4 methyltransferase encoding the catalytic subunit of the COMPASS complex, involved in epigenetic regulation of neuronal function and neurodegenerative disease pathogenesis.

View on Wiki →

No AI portrait yet

🧬 Gene Info

Gene Symbol	SETD1B
Full Name	SET Domain Containing 1B, Histone Lysine Methyltransferase
Chromosome	12q24.31
Protein Type	Transferase
Function	is a human gene encoding a histone H3 lysine 4 (H3K4) methyltransferase that functions as the catalytic subunit of the COMPASS (Complex of Proteins Associated with Set1) complex.
Molecular Weight	192 kDa
Amino Acids	755 aa
UniProt ID	Q9BRL5
Ensembl ID	ENSG00000146070
OMIM	612052
GeneCards	SETD1B
Human Protein Atlas	SETD1B
Associated Diseases	Alzheimer's disease, Parkinson's disease
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: SETD1B — AlphaFold Q9BRL5 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

SETD1B

gene · 3299 words

→

Pathway Diagram

graph TD
    SETD1B["SETD1B"]
    neurodegeneration["neurodegeneration"]
    SETD1B -->|"implicated_in"| neurodegeneration
    style SETD1B fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning SETD1B in their description or question text

No additional research found