gene

SLC34A3

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SLC34A3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

SLC34A3 encodes sodium-phosphate transporter 3 (NaPi-IIb), involved in phosphate homeostasis with emerging roles in brain function and neurodegeneration

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🧬 Gene Info

Gene Symbol	SLC34A3
Full Name	Sodium-Phosphate Transporter 3
Aliases	NaPi-IIb
Chromosome	9q34.3
Protein Type	Transporter
Function	is a membrane transport protein that plays a critical role in phosphate homeostasis.
Primary Expression	various brain regions[@bielohuby2017]:
UniProt ID	[Q8NCC9](https://www.uniprot.org/uniprot/Q8NCC9)
Ensembl ID	ENSG00000139433
OMIM	609226
GeneCards	SLC34A3
Human Protein Atlas	SLC34A3
Cortex	Neuronal and glial expression
Hippocampus	Dentate gyrus and CA regions
Associated Diseases	Alzheimer's disease, Parkinson's disease
Databases	GeneCards NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

SLC34A3 — Sodium-Phosphate Transporter 3

gene · 1418 words

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Pathway Diagram

graph TD
    SLC34A3["SLC34A3"]
    neurodegeneration["neurodegeneration"]
    SLC34A3 -->|"implicated_in"| neurodegeneration
    style SLC34A3 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning SLC34A3 in their description or question text

No additional research found