Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SLC41A1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
SLC41A1 is a magnesium transporter protein implicated in early-onset Parkinson's disease, renal magnesium wasting, and neuronal magnesium homeostasis critical for mitochondrial function
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| Gene Symbol | SLC41A1 |
| Full Name | Solute Carrier Family 41 Member 1 |
| Chromosome | 17q23 |
| Protein Type | Transporter |
| Function | is a member of the SLC41 family of magnesium transporters that plays a critical role in cellular magnesium homeostasis. |
| Primary Expression | Brain (substantia nigra), kidney, heart, liver, skeletal muscle |
| Amino Acids | 515 aa |
| UniProt ID | [Q9H3M4](https://www.uniprot.org/uniprot/Q9H3M4) |
| Ensembl ID | ENSG00000133043 |
| OMIM | 610264 |
| GeneCards | SLC41A1 |
| Human Protein Atlas | SLC41A1 |
| Associated Diseases | Parkinson's disease, Alzheimer's disease |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
SLC41A1["SLC41A1"]
neurodegeneration["neurodegeneration"]
SLC41A1 -->|"implicated_in"| neurodegeneration
style SLC41A1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
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Scientific analyses that reference this entity
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Experimental studies targeting or related to this entity
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Scientific publications cited in analyses involving this entity
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning SLC41A1 in their description or question text
No additional research found