gene

SLC7A3

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SLC7A3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

SLC7A3 gene encoding CAT3 - a high-affinity cationic amino acid transporter in brain development and function

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🧬 Gene Info

Gene Symbol	SLC7A3
Full Name	Cationic Amino Acid Transporter 3 (CAT3)
Aliases	SLC7A3 gene encoding CAT3
Chromosome	Xq28
Protein Type	Transporter
Function	is a human gene encoding a high-affinity cationic amino acid transporter protein.
Primary Expression	neural progenitor cells and newly differentiated neurons
UniProt ID	Q8WWI5
NCBI Gene ID	6534
Ensembl ID	ENSG00000165370
OMIM	300443
GeneCards	SLC7A3
Human Protein Atlas	SLC7A3
Associated Diseases	Alzheimer's disease, Parkinson's disease
Databases	GeneCards HPA STRING

🔮 Predicted Structure: SLC7A3 — AlphaFold Q8WWI5 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

SLC7A3 — Cationic Amino Acid Transporter 3

gene · 1730 words

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Genes

index · 271 words

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Pathway Diagram

graph TD
    SLC7A3["SLC7A3"]
    neurodegeneration["neurodegeneration"]
    SLC7A3 -->|"implicated_in"| neurodegeneration
    style SLC7A3 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found