TMAO

Understanding Entity Pages

This page aggregates everything SciDEX knows about TMAO: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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graph TD
    TMAO["TMAO"] -->|"activates"| NFKB["NFKB"]
    style NFKB fill:#1a2a3a,stroke:#81c784,stroke-width:1px,color:#fff
    TMAO["TMAO"] -->|"regulates"| TNF["TNF"]
    style TNF fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    TMAO["TMAO"] -->|"regulates"| IL6["IL6"]
    style IL6 fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    TMAO["TMAO"] -->|"regulates"| IL1B["IL1B"]
    style IL1B fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    TMAO["TMAO"] -->|"regulates"| ROS["ROS"]
    style ROS fill:#1a2a3a,stroke:#ffd54f,stroke-width:1px,color:#fff
    TMAO["TMAO"] -->|"associated"| ASTROCYTES["ASTROCYTES"]
    style ASTROCYTES fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    TMAO["TMAO"] -->|"involved in"| ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"]
    style ALZHEIMER_S_DISEASE fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
    Shexiang_Baoxin_Pill["Shexiang Baoxin Pill"] -->|"regulates"| TMAO["TMAO"]
    style Shexiang_Baoxin_Pill fill:#1a2a3a,stroke:#81c784,stroke-width:1px,color:#fff
    Bile_Acid_Synthesis["Bile Acid Synthesis"] -->|"regulates"| TMAO["TMAO"]
    style Bile_Acid_Synthesis fill:#1a2a3a,stroke:#81c784,stroke-width:1px,color:#fff
    style TMAO fill:#006494,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0,font-weight:bold