gene

TNN

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about TNN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for TNN Gene

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🧬 Gene Info

Gene Symbol	TNN
Full Name	Tenascin N
Chromosome	1q23.3
Protein Family	Tenascin
Function	It interacts with other ECM components, including fibronectin, laminin, and proteoglycans, to create a permissive environment for neurite outgrowth and synapse formation.
Primary Expression	the nervous system and has been implicated in various neurodegenerative diseases, including Alzheimer's disease (AD) and Parkinson's disease (PD)
Molecular Weight	240 kDa
UniProt ID	Q9C0B1
NCBI Gene ID	57123
Ensembl ID	ENSG00000132604
OMIM	608581
GeneCards	TNN
Human Protein Atlas	TNN
Cerebellum	Present in the molecular layer and Purkinje cell layer
Thalamus	Expression in specific thalamic nuclei
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: TNN — AlphaFold Q9C0B1 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (5)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

graph TD
    TNN["TNN"]
    neurodegeneration["neurodegeneration"]
    TNN -->|"implicated_in"| neurodegeneration
    style TNN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning TNN in their description or question text

No additional research found

TNN