Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about Tight Junction Proteins: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| Brain Arteriovenous Malformations | biomarker_for | disease | 0.85 |
| Blood-Brain Barrier Function | mediates | process | 0.85 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Betulinic Acid | upregulates | compound | 0.90 |
| Endoplasmic Reticulum Stress | downregulates | process | 0.85 |
| Dolutegravir | downregulates | drug | 0.80 |
| Cavernomas | associated_with | disease | 0.75 |
| AEP | degrades | protein | 0.75 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||