concept

UBA52

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about UBA52: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

14Connections
0Hypotheses
0Analyses
7Outgoing
7Incoming

No summary available yet. View on Wiki →

💡 Concept Info
NameUBA52
Key Genes/ProteinsMLKL, USP7, UBIQUITIN, AUTOPHAGY
Related DiseasesALS
Related PathwaysAutophagy

Wiki Pages (4)

Knowledge base pages for this entity

autophagy-lysosomal-alzheimers

mechanism · 3555 words

Ubiquitin Protein

protein · 946 words

USP7 Gene

gene · 898 words

MLKL Protein

protein · 620 words

Pathway Diagram

graph TD
    UBA52["UBA52"]
    UBA52 -->|"involved_in"| Autophagy["Autophagy"]
    UBA52 -->|"stabilizes"| ALS["ALS"]
    UBA52 -->|"stabilizes"| MLKL["MLKL"]
    UBA52 -->|"stabilizes"| UBIQUITIN["UBIQUITIN"]
    UBA52 -->|"stabilizes"| AUTOPHAGY["AUTOPHAGY"]
    UBA52 -->|"stabilizes"| USP7["USP7"]
    MLKL -->|"interacts"| UBA52
    USP7 -->|"modifies"| UBA52
    AUTOPHAGY -->|"stabilizes"| UBA52
    UBIQUITIN -->|"stabilizes"| UBA52

Outgoing (7)

TargetRelationTypeStr
Autophagyinvolved_inprocess0.95
ALSstabilizesdisease0.65
Autophagystabilizespathway0.60
MLKLstabilizesgene0.60
UBIQUITINstabilizesgene0.60

Incoming (7)

SourceRelationTypeStr
MLKLinteracts_withgene0.90
USP7modifiesgene0.90
USP7interacts_withprotein0.85
USP7stabilizesgene0.60
MLKLstabilizesgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found