protein

VE-cadherin

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about VE-cadherin: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

18Connections

0Hypotheses

0Analyses

14Outgoing

4Incoming

0Experiments

0Debates

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🔬 Protein Info

Gene Symbol	VE
Full Name	cadherin
Pathways	Reelin Secretion, VE-cadherin Trafficking
GeneCards	VE
Human Protein Atlas	VE
Interactions	ARF6, Exocyst Complex
KG Connections	14 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Pathway Diagram

graph TD
    VE_cadherin["VE-cadherin"] -->|"mediates"| Adherens_Junction_Remodeling["Adherens Junction Remodeling"]
    style Adherens_Junction_Remodeling fill:#1a2a3a,stroke:#ffd54f,stroke-width:1px,color:#fff
    VE_cadherin["VE-cadherin"] -->|"modulates"| Lymphatic_Permeability["Lymphatic Permeability"]
    style Lymphatic_Permeability fill:#1a2a3a,stroke:#ffd54f,stroke-width:1px,color:#fff
    VE_cadherin["VE-cadherin"] -->|"modulates"| Cytoskeletal_Remodeling["Cytoskeletal Remodeling"]
    style Cytoskeletal_Remodeling fill:#1a2a3a,stroke:#ffd54f,stroke-width:1px,color:#fff
    VE_cadherin["VE-cadherin"] -->|"regulates"| Reelin_Secretion["Reelin Secretion"]
    style Reelin_Secretion fill:#1a2a3a,stroke:#ffd54f,stroke-width:1px,color:#fff
    VE_cadherin["VE-cadherin"] -->|"interacts"| ARF6["ARF6"]
    style ARF6 fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    VE_cadherin["VE-cadherin"] -->|"interacts"| Exocyst_Complex["Exocyst Complex"]
    style Exocyst_Complex fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    VE_cadherin["VE-cadherin"] -->|"involved in"| VE_cadherin_Trafficking["VE-cadherin Trafficking"]
    style VE_cadherin_Trafficking fill:#1a2a3a,stroke:#ffd54f,stroke-width:1px,color:#fff
    TMEM16F["TMEM16F"] -->|"regulates"| VE_cadherin["VE-cadherin"]
    style TMEM16F fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
    ARF6_1["ARF6"] -->|"interacts"| VE_cadherin["VE-cadherin"]
    style ARF6_1 fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
    Exocyst_Complex_2["Exocyst Complex"] -->|"interacts"| VE_cadherin["VE-cadherin"]
    style Exocyst_Complex_2 fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    style VE_cadherin fill:#006494,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0,font-weight:bold

Outgoing (14)

Target	Relation	Type	Str
Adherens Junction Remodeling	mediates	process	0.95
Reelin Secretion	regulates	process	0.90
Cytoskeletal Remodeling	modulates	process	0.90
Lymphatic Permeability	modulates	phenotype	0.90
reelin secretion	regulates	biological_process	0.90
Exocyst Complex	interacts_with	protein	0.85
ARF6	interacts_with	protein	0.85
VE-cadherin Trafficking	involved_in	process	0.85
Blood-Brain Barrier	biomarker_for	brain_region	0.85
junctional remodeling	mediates	process	0.80
reelin secretion	mediates	process	0.80
ARF6	participates_in	protein	0.80
exocyst complex	participates_in	entity	0.80
reelin	regulates	protein	0.80

Incoming (4)

Source	Relation	Type	Str
TMEM16F	regulates	gene	1.00
ARF6	interacts_with	gene	0.90
Exocyst Complex	interacts_with	protein	0.90
Qingqi Liangying Formula	upregulates	drug	0.90

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity