Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about WDPCP: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
WDPCP protein involved in planar cell polarity, ciliogenesis, and autophagy regulation, with implications for neurodegenerative diseases.
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| Gene Symbol | WDPCP |
| Full Name | WD Repeat Containing Polypeptide |
| Chromosome | 2p15 |
| Protein Family | WD40 repeat protein family |
| Function | encodes a protein belonging to the WD40 repeat protein family, a large group of regulatory proteins characterized by conserved WD40 repeat motifs that form beta-propeller structures. |
| Molecular Weight | 79 kDa |
| Amino Acids | 724 aa |
| Exons | 14 |
| UniProt ID | Q8WZ73 |
| NCBI Gene ID | 51026 |
| Ensembl ID | ENSG00000143977 |
| GeneCards | WDPCP |
| Human Protein Atlas | WDPCP |
| Dishevelled (Dvl) | Cytoplasmic scaffold |
| Prickle (Pk) | Intracellular regulator |
| Associated Diseases | Alzheimer's disease, Parkinson's disease |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
WDPCP["WDPCP"]
neurodegeneration["neurodegeneration"]
WDPCP -->|"implicated_in"| neurodegeneration
style WDPCP fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning WDPCP in their description or question text
No additional research found