gene

WDR7

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about WDR7: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Gene profile: WDR7

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🧬 Gene Info

Gene Symbol	WDR7
Full Name	WD Repeat Domain 7
Chromosome	18q21.1
Function	Mitochondrial morphology control: WDR7 regulates mitochondrial dynamics by influencing fusion and fission processes.
Molecular Weight	68 kDa
Amino Acids	642 aa
Exons	21
Pathways	TGF-β
GeneCards	WDR7
Human Protein Atlas	WDR7
Highest Expression	Cerebral cortex, hippocampus, substantia nigra, cerebellum
Moderate Expression	Basal ganglia, thalamus, hypothalamus
Expression in Spinal Cord	Particularly in motor neurons
Cytoplasmic	Predominantly cytoplasmic, associated with cytoskeletal elements
Mitochondrial	Partial mitochondrial localization mediating mitochondrial function
Associated Diseases	neurodegeneration
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (4)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

graph TD
    WDR7["WDR7"]
    neurodegeneration["neurodegeneration"]
    WDR7 -->|"implicated_in"| neurodegeneration
    style WDR7 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning WDR7 in their description or question text

No additional research found