WNT10A

Understanding Entity Pages

This page aggregates everything SciDEX knows about WNT10A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

WNT10A encodes a member of the Wnt family of secreted signaling proteins involved in embryonic development, tissue homeostasis, stem cell biology, and increasingly recognized roles in neurodevelopment and neurodegeneration.

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flowchart TD
    N0["WNT10A"]
    N1["Ectodermal Dysplasia Syndromes"]
    N0 -->|"associated with"| N1
    N2["Tooth Agenesis"]
    N0 -->|"associated with"| N2
    N3["Glioblastoma"]
    N0 -->|"associated with"| N3
    N4["Ectodermal Organogenesis"]
    N0 -->|"participates in"| N4
    N5["Tissue Regeneration"]
    N0 -->|"participates in"| N5
    N6["Selective Tooth Agenesis"]
    N0 -->|"associated with"| N6
    N7["Hidradenitis Suppurativa"]
    N0 -->|"associated with"| N7
    N8["Cleft Lip with/without Cleft Palate"]
    N0 -->|"associated with"| N8
    N9["Fibrosis"]
    N0 -->|"associated with"| N9
    N10["Carcinogenesis"]
    N0 -->|"associated with"| N10
    N11["neurodegeneration"]
    N0 -->|"implicated in"| N11

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    class N1 disease
    class N2 disease
    class N3 disease
    class N6 disease
    class N7 disease
    class N8 disease
    class N9 disease