Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about WNT9A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
WNT9A is a Wnt signaling protein that activates canonical Wnt/β-catenin pathways, regulating nephron development, neural progenitor cell behavior, and showing altered expression in Alzheimer's disease.
| Gene Symbol | WNT9A |
| Full Name | WNT9A — Wnt Family Member 9A |
| Chromosome | 1q42.13 |
| Protein Type | Gene |
| Function | is a secreted signaling protein belonging to the Wnt family that plays essential roles in embryonic development, tissue patterning, and adult tissue homeostasis[@wntfamily2023]. |
| Amino Acids | 355 aa |
| Pathways | WNT, Wnt, wnt, Wnt pathway |
| NCBI Gene ID | Search NCBI |
| GeneCards | WNT9A |
| Human Protein Atlas | WNT9A |
| Associated Diseases | Alzheimer's disease, Parkinson's disease |
| Databases | GeneCardsUniProtHPASTRING |
Knowledge base pages for this entity
graph TD
WNT9A["WNT9A"]
neurodegeneration["neurodegeneration"]
WNT9A -->|"implicated_in"| neurodegeneration
style WNT9A fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| No outgoing edges | |||
| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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Multi-agent debates referencing this entity
No debates reference this entity