gene

adra2c

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about adra2c: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

4Connections
0Hypotheses
0Analyses
2Outgoing
2Incoming

No summary available yet. View on Wiki →

🧬 Gene Info
Gene SymbolADRA2C
Full NameAdrenoceptor Alpha 2C
Chromosome4p16.3
Primary Expressionthe central nervous system and peripheral tissues, playing crucial roles in regulating norepinephrine signaling, autonomic function, and stress respon
Amino Acids462 aa
PathwaysMAPK Pathway
UniProt ID[P21917](https://www.uniprot.org/uniprot/P21917)
Ensembl IDENSG00000141449
GeneCardsADRA2C
Human Protein AtlasADRA2C
Associated DiseasesAlzheimer's disease, Parkinson's disease
DatabasesGeneCardsNCBI GeneHPASTRING

Wiki Pages (15)

Knowledge base pages for this entity

adra2b Gene

gene · 1915 words

A2 Noradrenergic Neurons

cell · 1410 words

Alpha-2 Adrenergic Receptor Neurons

cell · 1385 words

Locus Coeruleus Alpha Adrenergic Neurons

cell · 1344 words

Dexmedetomidine Transdermal System (DMTS) for AD Agitation

clinical · 1335 words

Pathway Diagram

graph TD
    A["Regulatory elements"] --> B["adra2c gene"]
    B --> C["mRNA transcript"]
    C --> D["Protein product"]
    D --> E["Cellular function"]
    E --> F["Disease relevance"]
    B --> G["Variant effects"]
    G --> F
    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    class B gene
    class D protein

Outgoing (2)

TargetRelationTypeStr
ds-83b31ef18d49provides_data_fordataset1.00
benchmark_ot_ad_answer_key:ADRA2Cdata_indataset_row0.00

Incoming (2)

SourceRelationTypeStr
ds-83b31ef18d49data_indataset1.00
benchmark_ot_ad_answer_key:ADRA2Cdata_indataset_row0.00

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found