gene

arh

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about arh: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

2Connections
0Hypotheses
0Analyses
1Outgoing
1Incoming

No summary available yet. View on Wiki →

🧬 Gene Info
Gene SymbolARH
Full NameLDLR Adaptor Protein 1 (also known as ARH)
Chromosome1p36.22
Protein TypeAdaptor Protein
FunctionARH (also known as LDLRAP1 - LDL Receptor Adaptor Protein 1) encodes an adaptor protein that links the LDL receptor (LDLR) to clathrin-mediated endocytosis.
UniProt ID[Q9Y2T3](https://www.uniprot.org/uniprot/Q9Y2T3)
Ensembl IDENSG00000151552
OMIM605747
GeneCardsARH
Human Protein AtlasARH
Associated DiseasesNeurodegeneration
DatabasesGeneCardsNCBI GeneHPASTRING

Wiki Pages (8)

Knowledge base pages for this entity

LRP1B — Low Density Lipoprotein Receptor-Related Protein 1B

gene · 3338 words

SORL1 Protein

protein · 2914 words

VLDL Receptor

protein · 2760 words

LDLRAP1 — Low Density Lipoprotein Receptor Adaptor Protein 1

gene · 1463 words

LDL Receptor Protein

protein · 1288 words

Pathway Diagram

graph TD
    A["Regulatory elements"] --> B["arh gene"]
    B --> C["mRNA transcript"]
    C --> D["Protein product"]
    D --> E["Cellular function"]
    E --> F["Disease relevance"]
    B --> G["Variant effects"]
    G --> F
    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    class B gene
    class D protein

Outgoing (1)

TargetRelationTypeStr
benchmark_ot_ad_answer_key:ARHdata_indataset_row0.00

Incoming (1)

SourceRelationTypeStr
benchmark_ot_ad_answer_key:ARHdata_indataset_row0.00

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found