Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about neuronal aging: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| Neddylation | regulates | pathway | 0.95 |
| H4K16ac | associated_with | biomarker | 0.90 |
| DNA Damage | contributes_to | process | 0.90 |
| DNA Damage | risk_factor_for | mechanism | 0.90 |
| APP | associated_with | gene | 0.85 |
| DNA methylation clock drift | associated_with | mechanism | 0.70 |
| SIRT1 decline | associated_with | process | 0.70 |
| H4K16ac | biomarker_for | mechanism | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
neurodegeneration | 2026-04-10 | 7 hypotheses Top: 0.700
neurodegeneration | 2026-04-04 | 7 hypotheses Top: 0.790
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
closed · Rounds: 4 · Score: 0.67 · 2026-04-22
closed · Rounds: 4 · Score: 0.50 · 2026-04-21
closed · Rounds: 0 · Score: 0.48 · 2026-04-21
closed · Rounds: 0 · Score: 0.51 · 2026-04-21
closed · Rounds: 4 · Score: 0.73 · 2026-04-21
Hypotheses and analyses mentioning neuronal aging in their description or question text
No additional research found