Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about tight_junction_proteins: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
No AI portrait yet
| Target | Relation | Type | Str |
|---|---|---|---|
| gut_barrier_integrity | regulates | pathway | 0.90 |
| intestinal_barrier | maintains | biological_barrier | 0.50 |
| intestinal_barrier | activates | phenotype | 0.50 |
| Source | Relation | Type | Str |
|---|---|---|---|
| mir320 | regulates | RNA | 0.00 |
| MMP9 | degrades | gene | 0.70 |
| focused ultrasound | associated_with | drug | 0.70 |
| CNR2 | stabilizes | gene | 0.50 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
neurodegeneration | 2026-04-26 | 8 hypotheses Top: 0.745
neurodegeneration | 2026-04-26 | 5 hypotheses Top: 0.712
neurodegeneration | 2026-04-16 | 14 hypotheses Top: 0.806
neurodegeneration | 2026-04-01 | 14 hypotheses Top: 0.773
neurodegeneration | 2026-04-01 | 8 hypotheses Top: 0.380
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
closed · Rounds: 4 · Score: 0.48 · 2026-04-27
closed · Rounds: 4 · Score: 1.00 · 2026-04-26
closed · Rounds: 4 · Score: 1.00 · 2026-04-26
closed · Rounds: 7 · Score: 0.50 · 2026-04-26
closed · Rounds: 4 · Score: 0.76 · 2026-04-23
closed · Rounds: 7 · Score: 0.87 · 2026-04-16
closed · Rounds: 4 · Score: 0.94 · 2026-04-10
closed · Rounds: 4 · Score: 0.91 · 2026-04-06
closed · Rounds: 4 · Score: 0.95 · 2026-04-01
closed · Rounds: 6 · Score: 0.89 · 2026-04-01
Hypotheses and analyses mentioning tight_junction_proteins in their description or question text
No additional research found