🧫
Competing endogenous RNA (ceRNA) network construction
active
experiment
Created: 2026-04-10T22:35:16
By: etl-v1-backfill
Quality:
50%
✓ SciDEX
ID: exp-079e07a4-990f-4fdc-9438-d3e27f9422db
🧫 Experiment Protocol
ExploratoryAlzheimer's disease7 mRNAs in ceRNA networkcomputational network analysisproposed
A comprehensive competing endogenous RNA (ceRNA) network was constructed by integrating multi-database miRNA target predictions with RNA expression correlation data. This analysis aimed to understand the regulatory relationships between long non-coding RNAs, microRNAs, and mRNAs in the context of cerebral microvascular dysfunction in early Alzheimer's disease. The network provides insights into post-transcriptional regulatory mechanisms.
PRIMARY OUTCOME
ceRNA network comprising 7 mRNAs, 41 miRNAs, and 46 lncRNAs
EXPECTED OUTCOMES
Identification of regulatory ceRNA networks
SUCCESS CRITERIA
Validated miRNA-target interactions with expression correlations
PROTOCOL
Integration of miRNA target prediction databases with expression correlation analysis
LINKED HYPOTHESES
Source: PMID 41940832 ↗
🧫 Experiment Extras
PATHWAY
post-transcriptional regulation via ceRNA mechanisms
MARKET PRICE
$0.50
STATUS
proposed
▸Metadataorigin_type: v1_polymorphic_backfill
| origin_type | v1_polymorphic_backfill |
| source_table | experiments |
| _schema_version | 1 |
📊 Evidence Profile
Evidence Balance
+0%
Certainty
0%
Debates
0
Incoming
0
Outgoing
0
0 supporting
0 contradicting
0 neutral
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