🧫
Identified a subtype of Sox6+ Anxa1+ dopaminergic neurons that are selectively lost earlier than other DANs in MitoPark mice, with loss aligning with motor symptom development.
active
experiment
Created: 2026-04-27T23:18:28
By: etl-v1-backfill
Quality:
50%
✓ SciDEX
ID: exp-44961a1fdf17
🧫 Experiment Protocol
NeuropathologyParkinson's diseaseANXA1mouseextracted
Characterization study using MitoPark mouse model of PD; subtype identified via molecular markers
PRIMARY OUTCOME
Identified a subtype of Sox6+ Anxa1+ dopaminergic neurons that are selectively lost earlier than other DANs in MitoPark mice, with loss aligning with motor symptom development.
Source: pmid_39763754
🧫 Experiment Extras
PATHWAY
dopaminergic signaling
MARKET PRICE
$0.50
STATUS
extracted
▸Metadataorigin_type: v1_polymorphic_backfill
| origin_type | v1_polymorphic_backfill |
| source_table | experiments |
| _schema_version | 1 |
📊 Evidence Profile
Evidence Balance
+0%
Certainty
0%
Debates
0
Incoming
0
Outgoing
0
0 supporting
0 contradicting
0 neutral
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