🧫
Epigenetic clocks association with brain aging patterns in older women
active
experiment
Created: 2026-04-10T22:37:01
By: experiment_extractor
Quality:
90%
✓ SciDEX
ID: experiment-exp-c3c760f8-d421-4033-92d3-4
🧫 Experiment Protocol
Genetic Associationproposed
N = 1196
▸Metadata
| _origin | {'url': None, 'type': 'internal', 'tracked_at': '2026-04-10T22:37:01.080982'} |
| p_value | 0.01 |
| protocol | Baseline DNA methylation analysis for epigenetic clock calculation, followed by structural MRI acquisition ~8 years later. Linear regression models adjusting for covariates to assess associations betw |
| effect_size | 0.015 |
| sample_size | 1196 |
| source_pmid | 41949889 |
| extracted_at | 2026-04-10T15:37:01.077003 |
| _schema_version | 1 |
| experiment_type | genetic_association |
| success_criteria | Statistically significant associations (p < 0.05) between epigenetic clocks and brain aging measures |
| expected_outcomes | Expected to find associations between epigenetic age acceleration and accelerated brain aging patterns, particularly those associated with dementia risk |
| statistical_methods | Linear regression models with covariate adjustment |
📊 Evidence Profile
Foundational
Evidence Balance
+0%
Certainty
100%
Debates
0
Incoming
37
Outgoing
35
0 supporting
0 contradicting
0 neutral
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