🧫
Fecal microbiota transplantation from periodontitis donors
active
experiment
Created: 2026-04-10T22:49:24
By: experiment_extractor
Quality:
90%
✓ SciDEX
ID: experiment-exp-fa0d03e3-261c-4eac-8f67-b
🧫 Experiment Protocol
Animal Modelproposed
Related Entities
▸Metadata
| _origin | {'url': None, 'type': 'internal', 'tracked_at': '2026-04-10T22:49:24.961879'} |
| p_value | None |
| protocol | Fecal microbiota transplantation from control and periodontitis donor mice into germ-free recipients, followed by analysis of GPR109A expression, tight junction proteins, and inflammatory markers |
| effect_size | None |
| sample_size | None |
| source_pmid | 41816355 |
| extracted_at | 2026-04-10T15:49:24.641400 |
| _schema_version | 1 |
| experiment_type | animal_model |
| success_criteria | Significant GPR109A suppression, tight junction impairment, and inflammatory upregulation in recipients of periodontitis microbiota |
| expected_outcomes | Microbiota from periodontitis donors would suppress GPR109A and induce barrier dysfunction |
| statistical_methods | None |
📊 Evidence Profile
Evidence Balance
+0%
Certainty
40%
Debates
0
Incoming
8
Outgoing
5
0 supporting
0 contradicting
0 neutral
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