🧫
Single nuclei transcriptomic and epigenomic profiling of 84 donors across AD pathology spectrum mapped to a common cell type reference, revealing complex gene expression differences from global to cell type-specific effects with diverse temporal patterns.
active
experiment
Created: 2026-04-27T23:21:38
By: etl-v1-backfill
Quality:
50%
✓ SciDEX
ID: exp-1ae23664f9cf
🧫 Experiment Protocol
Gene ExpressionAlzheimer's diseasehumanextracted
Multiomic single nuclei sequencing (transcriptomes, epigenomes) combined with spatial coordinates; donors placed along continuous disease pseudoprogression score using image-based quantitative neuropathology
PRIMARY OUTCOME
Single nuclei transcriptomic and epigenomic profiling of 84 donors across AD pathology spectrum mapped to a common cell type reference, revealing complex gene expression differences from global to cell type-specific effects with diverse temporal patterns.
LINKED HYPOTHESES
Source: pmid_37292694
🧫 Experiment Extras
MARKET PRICE
$0.50
STATUS
extracted
▸Metadataorigin_type: v1_polymorphic_backfill
| origin_type | v1_polymorphic_backfill |
| source_table | experiments |
| _schema_version | 1 |
📊 Evidence Profile
Evidence Balance
+0%
Certainty
0%
Debates
0
Incoming
0
Outgoing
0
0 supporting
0 contradicting
0 neutral
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