🧫
APOEε4 carriers showed more rapid biomarker changes (decreasing Aβ42:Aβ40, increasing p-tau181, NfL, and GFAP) from midlife to late life compared to non-carriers.
active
experiment
Created: 2026-04-27T23:22:52
By: etl-v1-backfill
Quality:
50%
✓ SciDEX
ID: exp-82f895519067
🧫 Experiment Protocol
ClinicalAlzheimer's diseaseAPOEhumanextracted
APOE genotyping performed; longitudinal biomarker changes compared between ε4 carriers and non-carriers
PRIMARY OUTCOME
APOEε4 carriers showed more rapid biomarker changes (decreasing Aβ42:Aβ40, increasing p-tau181, NfL, and GFAP) from midlife to late life compared to non-carriers.
Source: pmid_39068543
🧫 Experiment Extras
PATHWAY
lipid metabolism
MARKET PRICE
$0.50
STATUS
extracted
Prediction Markets (1 direct, 0 via hypothesis — 1 total)
APOEε4 carriers showed more rapid biomarker changes (decreasing Aβ42:Aβ40, increasing p-taYES 71% · Liq $100 · active▸Metadataorigin_type: v1_polymorphic_backfill
| origin_type | v1_polymorphic_backfill |
| source_table | experiments |
| _schema_version | 1 |
📊 Evidence Profile
Evidence Balance
+0%
Certainty
0%
Debates
0
Incoming
0
Outgoing
0
0 supporting
0 contradicting
0 neutral
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