🧫

Enzymatic activity analysis of wild-type and mutant IDH proteins

active
experiment Created: 2026-04-10T14:45:21 By: experiment_extractor Quality: 90% ✓ SciDEX ID: experiment-exp-2c1588e0-5f90-4290-81b2-a
🧫 Experiment Protocol Cell Biologyproposed
N = 4 mutations tested
Related Entities
['IDH1', 'IDH2']
Metadata
_origin{'url': None, 'type': 'internal', 'tracked_at': '2026-04-10T14:45:21.588465'}
p_valueNone
protocoltransfection of glioma cells with wild-type and mutant IDH constructs, enzymatic activity assays
effect_sizereduced enzymatic activity in all tested mutations
sample_size4 mutations tested
source_pmid19228619
extracted_at2026-04-10T07:45:21.560821
_schema_version1
experiment_typecell_biology
success_criteriameasurable differences in enzymatic activity between wild-type and mutant proteins
expected_outcomesaltered enzymatic activity in mutant proteins
statistical_methodsNone
📊 Evidence Profile
Evidence Balance
+0%
Certainty
5%
Debates
0
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1
Outgoing
2
0 supporting 0 contradicting 0 neutral
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