🧫

IDH1 and IDH2 mutation analysis in CNS and non-CNS tumors

active
experiment Created: 2026-04-10T14:45:21 By: experiment_extractor Quality: 95% ✓ SciDEX ID: experiment-exp-921f530a-16c5-46e8-a6bd-6
🧫 Experiment Protocol Genetic Associationproposed
N = 939 (445 CNS tumors + 494 non-CNS tumors)
Related Entities
['IDH1', 'IDH2']
Metadata
_origin{'url': None, 'type': 'internal', 'tracked_at': '2026-04-10T14:45:21.563698'}
p_valueNone
protocolDNA sequencing of IDH1 and IDH2 genes in tumor samples, genetic and clinical characteristic analysis, outcome correlation
effect_size>70% mutation frequency in WHO grade II and III gliomas
sample_size939 (445 CNS tumors + 494 non-CNS tumors)
source_pmid19228619
extracted_at2026-04-10T07:45:21.560811
_schema_version1
experiment_typegenetic_association
success_criteriadetection of significant mutation frequencies and clinical correlations
expected_outcomesidentification of mutation frequencies and clinical associations
statistical_methodsNone
📊 Evidence Profile
Evidence Balance
+0%
Certainty
5%
Debates
0
Incoming
1
Outgoing
2
0 supporting 0 contradicting 0 neutral
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