Plasma p-tau217-Triggered Exosome Dosing Maximizes lncRNA-0021 Therapeutic Window
🧬 N/A
🏥 Alzheimer disease
💰 $44,000
⏱ 11mo
✅ 0.78
✨ 0.80
in-vivo
Expected: P-tau217-stratified dosing reduces amyloid and tau pathology by >30% and improves cognitive performa...
Theta-Gamma Coupling Restoration Through PV Interneuron Optogenetic Modulation
🧬 N/A
🏥 Alzheimer disease
💰 $50,000
⏱ 12mo
✅ 0.78
✨ 0.80
in-vivo
Expected: Closed-loop stimulation restores theta-gamma coupling (phase-amplitude coupling index restored to >8...
SCFA-GPR43-TREM2 Axis in Microglial Homeostasis Using Germ-Free Mouse Model
🧬 N/A
🏥 Alzheimer disease
💰 $38,000
⏱ 10mo
✅ 0.78
✨ 0.80
in-vivo
Expected: SCFA supplementation increases TREM2 expression and reduces amyloid plaque load by >30% in germ-free...
Vagus Nerve Alpha-Synuclein Propagation and Brainstem Involvement in PD
🧬 N/A
🏥 Parkinson disease
💰 $42,000
⏱ 14mo
✅ 0.78
✨ 0.80
in-vivo
Expected: Vagotomized mice show >50% reduction in p-Syn (Ser129) pathology in the ipsilateral DMV and demonstr...
Enteric Alpha-Synuclein Propagation and ENS Dysfunction in PD Mouse Model
🧬 N/A
🏥 Parkinson disease
💰 $48,000
⏱ 12mo
✅ 0.78
✨ 0.80
in-vivo
Expected: Alpha-synuclein pathology detected in vagus nerve and dorsal motor nucleus by 6 months post-injectio...