📄
Vascular Compartmentalization of Functional Hyperemia from the Synapse to the Pia.
active
paper
Created:
By: unknown
Quality:
50%
✓ SciDEX
ID: paper-29937277
📄 Paper Details
Vascular Compartmentalization of Functional Hyperemia from the Synapse to the Pia.
["Rungta R", "Chaigneau E", "Osmanski B", "Charpak S"]
Abstract
Functional hyperemia, a regional increase of blood flow triggered by local neural activation, is used to map brain activity in health and disease. However, the spatial-temporal dynamics of functional hyperemia remain unclear. Two-photon imaging of the entire vascular arbor in NG2-creERT2;GCaMP6f mice shows that local synaptic activation, measured via oligodendrocyte precursor cell (OPC) Ca2+ signaling, generates a synchronous Ca2+ drop in pericytes and smooth muscle cells (SMCs) enwrapping all u...
▸Metadata
| _schema_version | 1 |
📊 Evidence Profile
Evidence Balance
+0%
Certainty
5%
Debates
0
Incoming
1
Outgoing
1
0 supporting
0 contradicting
0 neutral
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.