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Fig. 9: The inhibition of NETs formation alleviated the disruption of TJs and AJs by act...
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Created: 2026-04-16T11:31:44
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Fig. 9Figure 9
The inhibition of NETs formation alleviated the disruption of TJs and AJs by activating Wnt3/β-catenin/TCF4 signaling pathway. A Expression levels of Wnt/β-catenin/TCF4 signaling proteins in the hippocampus were detected by Western blot (n = 6). B – H The quantification analysis of Wnt/β-catenin/TCF4 signaling proteins expression levels (n = 6). I Wnt3 is predominantly secreted by neurons in the hippocampal CA1 region of septic mice. J Quantification of the mean fluorescence intensity of Wnt3 in CA1 region (n = 6). NETs: Neutrophil extracellular traps; CLP: Cecal Ligation and Puncture; SAE: Sepsis-associated encephalopathy; BBB: Blood–brain barrier; TJs: Tight junctions; AJs: adherens junction (ns: no significance, * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001)
▸Metadata
| doi | |
| pmcid | PMC11917101 |
| _origin | {'url': 'https://www.ebi.ac.uk/europepmc/articles/PMC11917101/bin/12974_2025_3395_Fig9_HTML.jpg', 'type': 'external', 'tracked_at': '2026-04-16T11:31:44.325145'} |
| caption | The inhibition of NETs formation alleviated the disruption of TJs and AJs by activating Wnt3/β-catenin/TCF4 signaling pathway. A Expression levels of Wnt/β-catenin/TCF4 signaling proteins in the hip |
| paper_id | 40102948 |
| image_url | https://www.ebi.ac.uk/europepmc/articles/PMC11917101/bin/12974_2025_3395_Fig9_HTML.jpg |
| image_path | |
| description | |
| figure_label | Fig. 9 |
| figure_number | 9 |
| _schema_version | 1 |
| source_strategy | pmc_api |
| entities_mentioned |
📊 Evidence Profile
Evidence Balance
+0%
Certainty
0%
Debates
0
Incoming
0
Outgoing
1
0 supporting
0 contradicting
0 neutral
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