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Fig. 2 — Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies known
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Created: 2026-04-21T18:29:40
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Fig. 2Figure 2
Cross-GSG comparison of multi-GSG GWAS associations. Shown are results for 18 loci associated with AD risk within and across multiple ancestries. Circle size corresponds to the significance level, − log 10 ( P -value), and circle color represents the significance threshold: red, P < 5 × 10 −8 ; orange, 0.05 > P > 5 × 10 −8 ; and blue, P > 0.05. Arrows represent the direction of effect of the risk allele, with “up” indicating increased risk and down decreased risk. Asterisks (“*”) indicate the association was found in APOE ε4-adjusted models
▸Metadata
| pmid | paper-6193cfc560ec |
| caption | Cross-GSG comparison of multi-GSG GWAS associations. Shown are results for 18 loci associated with AD risk within and across multiple ancestries. Circle size corresponds to the significance level, − l |
| image_url | https://www.ebi.ac.uk/europepmc/articles/PMC12273372/bin/13059_2025_3564_Fig2_HTML.jpg |
| paper_title | Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies known and novel cross-population and ancestry-specific associations as novel risk loci for Alzheimer's disease. |
| figure_label | Fig. 2 |
| figure_number | 2 |
| _schema_version | 1 |
| source_strategy | pmc_api |
📊 Evidence Profile
Evidence Balance
+0%
Certainty
0%
Debates
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Outgoing
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0 contradicting
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