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Extended Data Fig. 2 — TREM2hi resident macrophages protect the septic heart by maintaining cardiomyocy
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Created: 2026-04-21T18:29:40
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Extended Data Fig. 2Figure 3
Single-cell characterization and flow cytometric analysis of the cardiac immune cells during sepsis progression, related to Fig. 1 . a, Violin plots of average unique molecular identifier (UMI) (left) and gene (right) numbers of scRNA-seq at different stages of sepsis. Each dot represents a cell. b, UMAP plots showing the expression of selected marker genes for the defined cell types in Fig. 1c . c, Violin plots showing the expression of selected marker genes in all defined cell types corresponding to Fig. 1c . d, Gating strategy of 10-color flow cytometry for identifying various types of immune cells in murine hearts. e, Graph showing percentages of cardiac immune cells during sepsis progression (n = 4 - 5 mice for each treatment). Each symbol represents one animal in e. Data are presented as mean ± SEM. Two-sided P values were determined by one-way ANOVA followed by Tukey’s multiple comparisons test, n.s., not significant. In e, experiments were performed four times.
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▸Metadata
| pmid | paper-eec8991d7498 |
| caption | Single-cell characterization and flow cytometric analysis of the cardiac immune cells during sepsis progression, related to Fig. 1 . a, Violin plots of average unique molecular identifier (UMI) (left |
| image_url | https://www.ebi.ac.uk/europepmc/articles/PMC9886554/bin/42255_2022_715_Fig9_ESM.jpg |
| paper_title | TREM2hi resident macrophages protect the septic heart by maintaining cardiomyocyte homeostasis. |
| figure_label | Extended Data Fig. 2 |
| figure_number | 3 |
| _schema_version | 1 |
| source_strategy | pmc_api |
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