| gap-synthetic-biolog | Gap in Seattle Hub lineage tracing: ML-guided Recorder and Editor Design | open | 0.81 | 0.81 | 2026-04-26 | 0 | | synthetic-biology-lineage-tracing |
| gap-synthetic-biolog | Gap in Seattle Hub lineage tracing: Molecular Recording and Cellular Memory Syst | open | 0.82 | 0.82 | 2026-04-26 | 0 | | synthetic-biology-lineage-tracing |
| gap-synthetic-biolog | Gap in Seattle Hub lineage tracing: Recording Neuroimmune and Degeneration-linke | open | 0.83 | 0.83 | 2026-04-26 | 0 | | synthetic-biology-lineage-tracing |
| gap-synthetic-biolog | Gap in Seattle Hub lineage tracing: Whole-organism Developmental Lineage Models | open | 0.78 | 0.78 | 2026-04-26 | 0 | | synthetic-biology-lineage-tracing |
| gap-collider-3895e26 | E2E direct open question a980051375 | open | 0.60 | 0.00 | 2026-04-26 | 0 | | |
| gap-20260426-9ef6444 | Mechanisms of microglial senescence in ALS: causative vs consequential roles | investigating | 0.85 | 0.00 | 2026-04-26 | 0 | | als |
| gap-debate-20260426- | What blood-brain barrier permeability changes serve as early biomarkers for neur | investigating | 0.90 | 0.00 | 2026-04-26 | 0 | | neurodegeneration |
| gap-debate-20260426- | Blood-brain barrier permeability changes as early biomarkers for neurodegenerati | investigating | 0.90 | 0.00 | 2026-04-26 | 0 | | neurodegeneration |
| gap-gut-brain-pd-202 | Gut-Brain Axis in Parkinson's Disease: Molecular Mechanisms, Neuroinflammation, | partially_addressed | 0.90 | 0.00 | 2026-04-26 | 0 | | neurodegeneration |
| gap-20260426-010545 | What is the role of gut microbiome-brain interactions in Parkinson's disease pat | investigating | 0.90 | 0.00 | 2026-04-26 | 0 | | neurodegeneration |
| gap-debate-20260426- | Blood-brain barrier permeability changes as early biomarkers for neurodegenerati | investigating | 0.90 | 0.00 | 2026-04-26 | 0 | | neurodegeneration |
| gap-debate-20260426- | What blood-brain barrier permeability changes serve as early biomarkers for neur | investigating | 0.80 | 0.00 | 2026-04-26 | 0 | | neurodegeneration |
| gap-debate-20260426- | What blood-brain barrier permeability changes serve as early biomarkers for neur | resolved | 0.80 | 0.00 | 2026-04-26 | 0 | | neurodegeneration |
| gap-debate-20260426- | test question | open | 0.50 | 0.00 | 2026-04-26 | 0 | | neurodegeneration |
| gap-debate-20260426- | test question | open | 0.50 | 0.00 | 2026-04-26 | 0 | | neurodegeneration |
| gap-bbb-permeability | Blood-brain barrier permeability changes as early biomarkers for neurodegenerati | partially_filled | 0.80 | 0.00 | 2026-04-26 | 0 | | neurodegeneration |
| gap-20260426-002803 | What blood-brain barrier permeability changes serve as early biomarkers for neur | investigating | 0.90 | 0.00 | 2026-04-26 | 0 | | neurodegeneration |
| gap-20260426-001933 | How do gut microbiome-brain interactions contribute to Parkinson Disease pathoge | investigating | 0.90 | 0.00 | 2026-04-26 | 0 | | neurodegeneration |
| gap-20260426-001521 | What blood-brain barrier permeability changes serve as early biomarkers for neur | investigating | 0.90 | 0.00 | 2026-04-26 | 0 | | neurodegeneration |
| gap-20260426-001501 | Blood-brain barrier permeability changes as early biomarkers for neurodegenerati | investigating | 0.90 | 0.00 | 2026-04-26 | 1 | 2026-04-26 | neurodegeneration |
| gap-20260425234323 | Microglial senescence in Alzheimer and Parkinson disease progression | partially_addressed | 0.85 | 0.00 | 2026-04-25 | 0 | | neurodegeneration |
| gap-20260425-225600 | How does gut microbiome dysbiosis contribute to neuroinflammation and neurodegen | investigating | 0.90 | 0.00 | 2026-04-25 | 0 | | neurodegeneration |
| gap-20260425-225305 | How does gut microbiome dysbiosis contribute to neuroinflammation and neurodegen | resolved | 0.90 | 0.00 | 2026-04-25 | 0 | | neurodegeneration |
| gap-test-20260425-22 | Test | open | 0.90 | 0.00 | 2026-04-25 | 0 | | neurodegeneration |
| gap-20260425-224724 | How does gut microbiome dysbiosis contribute to neuroinflammation and neurodegen | investigating | 0.95 | 0.00 | 2026-04-25 | 1 | 2026-04-26 | neurodegeneration |
| gap-7a2dd5c1 | Characterize SPHK1 interactions and mechanisms | open | 0.60 | 0.58 | 2026-04-25 | 0 | | neurodegeneration |
| gap-epi-clock-biomar | Epigenetic clocks as biomarkers for Alzheimer disease and neurodegeneration | resolved | 0.85 | 0.00 | 2026-04-25 | 0 | | neurodegeneration |
| gap-20260425215446 | What are the mechanisms by which microglial senescence contributes to ALS pathol | partially_filled | 0.85 | 0.00 | 2026-04-25 | 0 | | neurodegeneration |
| gap-20260425-213240- | Does APOE4 worsen microglial lipid handling? | resolved | 0.60 | 0.00 | 2026-04-25 | 0 | | neurodegeneration |
| gap-20260425-200805- | test question | open | 0.50 | 0.00 | 2026-04-25 | 0 | | neurodegeneration |
| gap-20260425-200805- | test question | open | 0.50 | 0.00 | 2026-04-25 | 0 | | neurodegeneration |
| gap-20260425-195701- | Does tau-directed lysosomal rescue alter microglial stress signaling? | resolved | 0.60 | 0.00 | 2026-04-25 | 0 | | neurodegeneration |
| gap-20260425-195436- | Can microglial lipid droplet reversal reduce APOE4-associated neurotoxicity? | open | 0.80 | 0.00 | 2026-04-25 | 0 | | neurodegeneration |
| gap-20260425-195324- | Does APOE4-driven microglial lipid metabolism create a tractable intervention po | resolved | 0.70 | 0.00 | 2026-04-25 | 0 | | neurodegeneration |
| gap-immunology-aging | Vaccine-induced Immune Memory Durability in Older Adults | open | 0.71 | 0.71 | 2026-04-25 | 0 | | immunology-aging-memory |
| gap-immunology-aging | Bone-marrow and Stromal Niches that Maintain Immune Memory | open | 0.65 | 0.65 | 2026-04-25 | 0 | | immunology-aging-memory |
| gap-immunology-aging | CD4/Tfh Help and Germinal-center Memory in Older Adults | open | 0.52 | 0.52 | 2026-04-25 | 0 | | immunology-aging-memory |
| gap-immunology-aging | Metabolic Maintenance of Immune Memory with Age | open | 0.77 | 0.77 | 2026-04-25 | 0 | | immunology-aging-memory |
| gap-immunology-aging | Epigenetic Programs Behind Memory-cell Reversal | open | 0.71 | 0.71 | 2026-04-25 | 0 | | immunology-aging-memory |
| gap-immunology-aging | Human Intervention Trials Targeting Immune-memory Aging | open | 0.71 | 0.71 | 2026-04-25 | 0 | | immunology-aging-memory |
| gap-immunology-aging | Tissue-resident Memory T Cells Across Aging Niches | open | 0.67 | 0.67 | 2026-04-25 | 0 | | immunology-aging-memory |
| gap-immunology-aging | Peripheral Immune Memory at the Neuroimmune Interface | open | 0.82 | 0.82 | 2026-04-25 | 0 | | immunology-aging-memory |
| gap-immunology-aging | Tissue-specific Atlas Coverage Beyond Blood | open | 0.76 | 0.76 | 2026-04-25 | 0 | | immunology-aging-memory |
| gap-immunology-aging | Sex, Ancestry, and Exposure Heterogeneity in Immune-memory Aging | open | 0.85 | 0.85 | 2026-04-25 | 0 | | immunology-aging-memory |
| gap-immunology-aging | CMV-driven Memory Inflation and Immunosenescence | open | 0.54 | 0.54 | 2026-04-25 | 0 | | immunology-aging-memory |
| gap-immunology-aging | Trained Immunity, Innate Memory, and Inflammaging | open | 0.74 | 0.74 | 2026-04-25 | 0 | | immunology-aging-memory |
| gap-human-brain-cell | [landscape-gap] Brain Region-Specific Cell Atlases: Many subcortical regions (th | open | 0.79 | 0.81 | 2026-04-25 | 0 | | human-brain-cell-types |
| gap-human-brain-cell | [landscape-gap] Disease-Associated Cell Type Vulnerability: Causal direction bet | open | 0.76 | 0.79 | 2026-04-25 | 0 | | human-brain-cell-types |
| gap-human-brain-cell | [landscape-gap] Developmental Cell Type Trajectories: Continuous developmental a | open | 0.75 | 0.78 | 2026-04-25 | 0 | | human-brain-cell-types |
| gap-human-brain-cell | [landscape-gap] Cell Type Connectivity & Electrophysiology: Human Patch-seq data | open | 0.82 | 0.84 | 2026-04-25 | 0 | | human-brain-cell-types |