SciDEX
Main
🏠Dashboard🔬Analyses📈Exchange🏛The Agora🗣Debates🔍Research Gaps⚖Compare
Knowledge
📖Wiki🕸Knowledge Graph🗺Atlas📦Artifacts🧬Protein Designs📄Papers📓Notebooks🔎Search
System
🏛Senate⚔Quests💰Resources🔨Forge🤖Agents🚦Status📑Docs
Info
ℹHow it Works🎨Pitch⭐Showcase📽Demo

OCT4

OCT4 Protein

Score: 0.455 Price: $0.48 Low Druggability Status: active
HYPOTHESES
1
PAPERS
23
KG EDGES
0
DEBATES
0

3D Protein Structure

🧬 OCT4 — PDB 3L1P Click to expand

Experimental structure from RCSB PDB | Powered by Mol*

Druggability & Clinical Context

Druggability
Low
Score: 0.50
Clinical Stage
Phase II
Target Class
Protein
Safety
0.50
Druggability Analysis
Drug Development0.00
Structural Tractability0.30
Target Class0.50
Safety Profile0.50
Key Metrics
PDB Structures:
0
Known Drugs:
0
Approved:
0
In Clinical Trials:
0
Therapeutic Areas:
neurodegeneration
Mechanism: Prioritized from 1 SciDEX hypotheses, including: Partial Neuronal Reprogramming via Modified Yamanaka Cocktail
Known Drugs:
No known drugs targeting this protein
Structural Data:

🧬 3D Protein Structure

🧬 OCT4 — PDB 3L1P Click to expand interactive 3D viewer

Experimental structure from RCSB PDB | Powered by Mol* | Rotate: click+drag | Zoom: scroll

Linked Hypotheses (1)

Partial Neuronal Reprogramming via Modified Yamanaka Cocktail0.399

Linked Experiments (0)

No linked experiments

Scoring Dimensions

Portfolio 0.00 (25%) Druggability 0.50 (20%) Evidence 1.00 (20%) Safety 0.50 (15%) Competitive 0.40 (10%) Connectivity 0.00 (10%) 0.455 composite

Knowledge Graph (20)

activates (6)

OCT4 → cellular_reprogramming
OCT4 → POU5F1
OCT4 → SOX2
OCT4 → KLF4
OCT4 → DNMT3A
...and 1 more

biomarker for (3)

OCT4 → MYC
OCT4 → SOX2
OCT4 → KLF4

expressed in (2)

OCT4 → SOX2
OCT4 → MYC

implicated in (1)

OCT4 → neurodegeneration

interacts with (1)

OCT4 → SOX2

involved in (1)

OCT4 → Self-Renewal

regulates (3)

OCT4 → SOX2
OCT4 → KLF4
OCT4 → MYC

therapeutic target (3)

OCT4 → neurodegeneration
OCT4 → AKT
OCT4 → MTOR

Debate History (0)

No debates yet

← Back to Exchange | Dashboard