| Gene Symbol | KLF4 |
| Full Name | Kruppel-Like Factor 4 |
| Chromosome | 9q31.2 |
| Protein Type | Transcription Factor |
| Function | Cell cycle control: Represses proliferation genes (c-Myc, cyclin D1) while activating cell cycle inhibitors (p21, p27) |
| Primary Expression | High in brain, GI tract, endothelial cells |
| Amino Acids | 483 aa |
| Pathways | Akt, Amyloid, Epigenetic, Neurogenesis, Nf-Kb |
| UniProt ID | O43474 |
| NCBI Gene ID | 9312 |
| Ensembl ID | ENSG00000109576 |
| OMIM | 602253 |
| GeneCards | KLF4 |
| Human Protein Atlas | KLF4 |
| Protein Class | C2H2 zinc-finger transcription factor |
| Associated Diseases | Atherosclerosis, Inflammation, Ms, Pluripotency, Senescence, Stroke |
| Interactions | POU5F1, SOX2, P38, JUND, JUN, OCT4 |
| KG Connections | 247 knowledge graph edges |
| Databases | GeneCardsHPASTRING |